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Clinicaltrials.gov was searched for registered study protocols. The search phrases “palmitoylethanolamide” and “suffering” resulted in thirteen entries, of which three had been concluded. None of them fulfilled our eligibility conditions.This is the preview of membership articles, log in via an establishment to examine obtain. Access this s
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2015). These scientific studies, taken collectively, advise that, Despite the fact that a direct activation of GPR55 or PPAR‐α takes place, PEA can create its anti‐inflammatory action during the gut also by means of indirect activation of CB1 and CB2 receptors, in all probability as a result of the ability of the compound to potentiate the act
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